Sugammadex

Sugammadex is used to reverse neuromuscular blockade after administration of the amino steroid non-depolarizing neuromuscular-blocking agents such as Vecuronium or Rocuronium. It is the first selective relaxant binding agent (SRBA). Sugammadex Sodium is the sodium salt form of the biologically inert, selective relaxant binding agent (SRBA) sugammadex, a modified, anionic cyclodextrin derivative containing a hydrophilic exterior and a hydrophobic core, with neuromuscular blocking drug (NMBD) reversal activity. Sugammadex Related Standards for Research Projects  Sugammadex is not only prone to degradation but traces of degradation impurities affect and change the colour to yellowish brown and makes it unacceptable in quality. Therefore, it is crucial to carefully select the process to prepare pure Sugammadex sodium. It has been reported that the generation of impurities and obtaining less pure compounds are major concerns with Sugammadex. Preparation of chloro gamma cyclodextrine int...